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The recovery coordinator should have a complete and current copy of the plan stored off-site, possibly at home. The backup coordinator should also have a copy stored off-site. One printed copy of the plan, along with a CD or diskette copy of the entire plan (possibly both) should be stored at an off-site location, most likely at the DR site itself. If there is a secure on-site location that the coordinator and the backup have access to, two copies should be stored there. Each recovery team leader and a single designated backup should have a copy of that team s part of the plan. There is no reason, for example, for the application recovery team to have a copy of the logistics team s plan. It does them no good to do so. All plan distribution and recovery is the responsibility of the recovery coordinator.

That s it. No more copies than that. Plans should not be ubiquitous. The key people should know about the plan, know where to find copies, and know the procedure to get their hands on them. The military calls this need to know access, and it seems to be the best approach for DR plan distribution.

With the monomers listed in Table 11.1, it is possible to create very narrow pH gradients, using one buffering species and one titrating species. For example, 3-morpholinopropylacrylamide (pK 7.0) used as a buffer, and 2-acrylamido-2methylpropanesulfonic acid used as a titrant can be cast so that the nal pH gradient covers the pH 6.5 7.5 range. The nal pH range will be linear between pK 0.5 and pK 0.5 for the buffering species. IPGs with such narrow pH ranges are used for very high pI resolution. Isoelectric focusing on such narrow pH range IPG gels have been used for the diagnosis of hemoglobinopathies, such as b-thalassemia, which is a recessive genetic disease. Figure 11.7 shows a comparison of IPG and carrier ampholyte gels used to separate hemoglobins present in 18-week-old fetal cord blood of normal and thalassemic fetuses.10 A normal fetus will possess three types of hemoglobin at 18 weeks: fetal hemoglobin (HbF), acetylated fetal hemoglobin (HbFac), and adult hemoglobin (HbA). If the fetus is homozygous for b-thalassemia, no HbA is present at 18 weeks. The electropherograms show that the IPG system allows the clear resolution of the HbA and HbFac bands, while the carrier ampholyte system yields a single band containing both HbA and HbFac. Thus the introduction of highresolution IPGs has allowed the early diagnosis of the disease using routinely obtainable blood samples. A second example of the improvements in isoelectric focusing generated by the introduction of IPG gels is shown in Figure 11.8, where protein samples obtained from bean seeds are subjected to IEF for up to 12 h, using carrier ampholytes and immobilized pH gradients.11 In principle, proteins focused at their isoelectric pH values are not subject to changes in position with time, since IEF is a steady

Another area where we disagree with conventional wisdom is in who the target audience for the plan is. Many experts on the subject have said that a DR plan should be written so that anyone from the most experienced system administrator all the way down to the CEO could pick up a copy of the plan and run with it. While a plan probably could be written this way, it would almost certainly result in a separate disaster. As much as he might want to take an active role in the recovery, it is not appropriate for the CEO to sit down at a keyboard during a disaster and work the recovery. Even in the unlikely event that he has the experience necessary to lead the recovery, he probably has other things that he should be doing. He should leave the recovery efforts to experienced people who have done this before.

9.6. Request for Proposal (RFP) or specifications document. 9.6.1. Interest and spirit of an RFP . . . . . . . . . . . . . . 9.6.2. Myths: standard questionnaire + one-stop supplier . 9.6.3. Key points in an RFP for application integration . . 9.7. Presentations from the candidates . . . . . . . . . . . . .